Analysis of L-asparaginase Related Adverse Reaction
نویسندگان
چکیده
منابع مشابه
L-Asparaginase from Erwinia carotovora
The physicochemical properties of the antileukemic Lasparaginase from Erwinia carotovora have been studied and compared with those of the corresponding clinically effective enzyme from Escherichia coli B. Although both enzymes are tetramers with similar molecular weight, the amino acid compositions are distinctly different and the Erwinia enzyme is more basic as judged by polyacrylamide electro...
متن کاملImmunological responses to L-asparaginase.
In a series of 40 patients treated with L-asparaginase for various neoplastic diseases, 6 patients had generalized anaphylactic reactions to L-asparaginase. Each of these reactors had antibodies detectable by passive hemagglutination, but precipitins were detectable in only one of this group of six patients. That patient had received two courses of the enzyme. 1 wk after the anaphylactic reacti...
متن کاملThe molecular perspective: l-asparaginase.
The Oncologist 2005;10:238–239 www.TheOncologist.com Correspondence: David S. Goodsell, Ph.D., Associate Professor, The Scripps Research Institute, Department of Molecular Biology, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. Telephone: 858-784-2839; Fax: 858-784-2860; e-mail: [email protected] Website: http://www.scripps.edu/pub/goodsell Received January 5, 2005; accepted...
متن کاملAn Unreported Clindamycin Adverse Reaction: Wrist Monoarthritis
Clindamycin is a lincosamide antibiotic which is approved for the treatment of anaerobic, streptococcal and staphylococcal infections. There has been an increased interest in the use of clindamycin since it achieves high intracellular levels in phagocytic cells, high levels in bone and appears to have an antitoxin effect against the toxin elaborating strains of streptococci and staphylococci. C...
متن کامل[Adverse reactions to L-asparaginase in children with acute lymphatic leukemia].
BACKGROUND The low notification of Adverse Drug Reactions (ADR) underscores the need for pharmacological surveillance systems that allow their detection, evaluation, prevention and registry especially in patients receiving multiple medications. AIM To communicate the ADR observed with the use E coli asparaginase (E coli ASP) in children with Acute Lymphatic Leukemia (ALL). PATIENTS AND METH...
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ژورنال
عنوان ژورنال: Korean Journal of Clinical Pharmacy
سال: 2017
ISSN: 1226-6051,2508-786X
DOI: 10.24304/kjcp.2017.27.3.143